Both players were already expected to miss this week, and that was confirmed with the release of the official injury report.
Maye is dealing with an ankle injury that should keep him sidelined for a number of weeks while Moore suffered a concussion in last week's game and will hopefully return for the team's London game in Week 5.
Fellow wide receiver Jeff Smith is also out with a concussion that he sustained in a car accident this past week.
The other three inactives were all healthy scratches in running back La'Mical Perine, cornerback Jason Pinnock, and defensive lineman Tim Ward. Perine was listed as questionable with an illness, but was likely going to be inactive regardless.
Marcus Maye and Elijah Moore are notable names on the NY Jets injury report
Although they were expected, Maye and Moore's absences will certainly be felt by the Jets. Maye's absence, in particular, leaves the Jets very thin at safety.
The team did just activate Ashtyn Davis and Sharrod Neasman off the injured reserve, but both players will be limited today, per head coach Robert Saleh.
That will leave Adrian Colbert and Jarrod Wilson as the only other safeties on the Jets roster. Colbert has started the last two weeks in place of the injured Lamarcus Joyner while Wilson has started 28 games over the last two years in Jacksonville.
With Moore sidelined, 2020 second-round pick Denzel Mims will be active for only the second time this season. He figures to play a somewhat significant role as the only backup outside receiver behind Corey Davis and Keelan Cole.
One other notable change to the inactive list sees defensive end Tim Ward as a healthy scratch for the first time this year. In his place, rookie defensive tackle Jonathan Marshall is active and set to make his NFL debut.
The Jets take on the Titans starting at 1 p.m. ET on CBS.