James Conner, Arizona Cardinals | 39.3 fantasy points
After Chase Edmonds had to leave the game early against the San Francisco 49ers due to a sprained ankle and did not return, James Conner totaled 21 carries for 96 yards and two touchdowns.
Additionally, Conner caught all five of his targets for 77 receiving yards and another touchdown. Conner marked his season-best with 173 scrimmage yards.
Jonathan Taylor, Indianapolis Colts | 33.0 fantasy points
Jonathan Taylor had a shining moment in the game against the NY Jets. With 19 carries for 172 yards and two touchdowns, he not only marked his season-best performance but also his second-best career performance.
Nick Chubb, Cleveland Browns | 29.3 fantasy points
After missing two games due to injury and a not-so-good performance against the Pittsburgh Steelers, Nick Chubb makes an impressive return. He needed 14 carries and 137 yards for his two touchdowns.
Ezekiel Elliott, Dallas Cowboys | 12.6 fantasy points
12.6 fantasy points and then a loser? Definitely yes. With 10 carries for 51 yards and no touchdowns, Ezekiel Elliott turned in his second-worst performance of the season after the season-opening loss to the Tampa Bay Buccaneers.
Elliott was forced to leave the game briefly with knee problems but quickly returned. Nevertheless, he was unable to make a major impact on the game.
Austin Ekeler, Los Angeles Chargers | 11.2 fantasy points
Austin Ekeler had 17 carries for 59 rushing yards against the Philadelphia Eagles, as well as three receptions on three targets for 23 receiving yards.
He did not score a touchdown. It marked the second time this season Ekeler fell short of 100 scrimmage yards with no touchdowns.
Aaron Jones, Green Bay Packers | 5.3 fantasy points
12 carries for 53 rushing yards is actually not that bad. However, Aaron Jones didn't catch any of his two targets and also remained without a touchdown. This means the second-worst performance of the season after the opening loss to the New Orleans Saints.