The Jets fell short against the Indianapolis Colts on Thursday Night Football losing by a final score of 45-30 in a game that felt more lopsided than its final score would indicate.
The big question surrounding the Jets is who their starting quarterback will be come Sunday. Will it be a returning Zach Wilson, the exciting Mike White, or even the veteran Josh Johnson? All options remain open at the time of writing.
As for the Bills, they'll be hoping to rebound following an embarrassing loss to a banged-up Jacksonville Jaguars team in Week 9.
Which team will emerge as the victors in this divisional matchup?
NY Jets vs. Buffalo Bills Odds Week 10
According to WynnBet, the Bills are the 13-point favorites on the road against the Jets. The Bills' moneyline for the game is currently set at -750 while the Jets are the underdogs at +525.
The total over/under for the game is set at 48.0 points.
NY Jets vs. Buffalo Bills Prediction Week 10
This is a game the Bills absolutely should win. But then again, they should have won against the Jaguars. And both the Tennessee Titans and Cincinnati Bengals should have beaten the Jets.
The NFL is weird sometimes. Especially if you're a good team in the AFC.
Nonetheless, the Bills remain the heavy favorites here for a reason. They have a much better overall roster complete with a dynamic offense and a talented defense full of notable players.
Meanwhile, the Jets aren't even sure who their starting quarterback will be on Sunday, at least at the time of writing.
As tempting as it is to go with the Mike White magic or a returning Zach Wilson aided by an offensive supporting cast playing some good football at the moment, the safe bet is to pick Buffalo.
The Bills are the better team. And in this case, let's just assume the better team wins, regardless of who is playing quarterback at MetLife Stadium on Sunday.
Final score of 31-20.